La leishmaniose viscerale infantile [a'propos de 40 cas]

Currently increasing in Morrocco, the infantile visceral leishmaniasis is a serious health problem Based on a retrospective study of forty cases of infantile visceral leishmaniasis managed at the pediatric service 3, from 1985 to 1994, we tried to point out the epidemiological, clinical, therapeutical and evolutive field of this affection in our country. These forty cases are distributed into 26 boys and 14 girls whose ages oscillate between 9 months and 12 years with an average of 4 years Most of them originate from the northern region of the country. The clinical manifestations included fever [100%], weight loss [67%], enlargement of the spleen [97%] enlargement of the liver [60%], hemorrhagic syndrome [30%] with severe anenlia and Jaundice [15%]. Diagnosis certitude was established by the bone marrow study in 33 out of 40 patients or by indirect immunofluorescence in 16 out of 19 patients. Therapy is based on the use of Glucantime' [37 cases] and Lomidine' [3 cases] in one or several cures. Complete recovery was achieved in 33 patients after one cure. The severity of this disease and cost of management necessitate an earlier, diagnosis, intensive treatment and a prophylaxis against leishmaniasis imperative

fibrose pulmonaire idiopathique [A' propos d'un cas]

The idiopathic pulmonary fibrosis is a rare affection in pediatrics pathology. It is a chronic disease that has evolved throughout a small period to reach death due to the respiratory inflammation. Hamman and Rich as a diagnostic of exclusion which makes the diagnostic difficult. The diagnostic of IPF is confirmed only by histologic evaluation, since it is mainly dependent on the interrogative, a clinical test and paraclinical arguments. The diagnostic which last a long period is harmful since the average of survival is less than 5 years. The medical treatment depends on the prescription of corticoids and eventually over those immunosuppressors. This treatment is relatively less efficient rapid, in this way a pulmonary transplantation should be considered. This Work was incited by a case of IPF, diagnosed after child's death. This child has benefited with a large therapy. Nonetheless, he died by respiratory insufficiency. In order to understand this affection disease, we have created a literary magazine of the IPF so that a precocious and an adequate knowledge of this mortal affection would be taken into consideration and acknowledged